Category Archives: New Research

Pathophysiological changes that affect drug disposition in protein-energy malnourished children

Oshikoya KA, Senbanjo IO. In-spite of abundant literature on the epidemiology and management of Protein Endery Malnutrition (PEM), focus on metabolism and therapeutic drug monitoring is lacking. This review discussed the pathophysiological changes in children with PEM that may affect the disposition of drugs frequently used for their treatment. This review has established abnormal disposition […]

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Food and Nutrition Bulletin issue on Management of Moderate Malnutrition

The Food and Nutrition Bulletin, vol 30, No 3 (2009) Supplement published in September, 2009, featured articles mainly on Managment of children with Moderate Malnutrition and other related topics. Find below topics of articles in this issue and link to the Food and Nutrition Bulletin website to access full articles. Dietary management of moderate malnutrition: […]

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A Large-Scale Distribution of Milk-Based Fortified Spreads: Evidence for a New Approach in Regions with High Burden of Acute Malnutrition

Isabelle Defourny, Andrea Minetti, Ge´za Harczi, Ste´phane Doyon, Susan Shepherd, Milton Tectonidis, Jean-Herve´ Bradol, Michael Golden This study demonstrated the potential for distribution of fortified spreads to reduce the incidence of severe wasting in large population of children 6–36 months of age in a District of the Maradi Region, Niger. This study evaluated a large-scale […]

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Probiotics and prebiotics for severe acute malnutrition (PRONUT study): a double-blind efficacy randomised controlled trial in Malawi

Kerac M, Bunn J, Seal A, Thindwa M, Tomkins A, Sadler K, Bahwere P, Collins S. In Malawi, Synbiotic2000 Forte did not improve severe acute malnutrition outcomes. The aim of this study was to assess the clinical and nutritional efficacy of a probiotic and prebiotic functional food for the treatment of severe acute malnutrition in […]

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Prognostic Accuracy of WHO Growth Standards to Predict Mortality in a Large-Scale Nutritional Program

This study by Lapidus and colleagues showed that among children being treated for malnutrition in Niger, Weight-for-Height indicators calculated using WHO standards were more accurate for predicting mortality risk than those calculated using the NCHS reference. The findings are of great significance because it means that more children at risk of dying can be identified […]

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Should India use Commercially Produced Ready to use Therapeutic Foods (RUTF) for Severe Acute Malnutrition (SAM)

In India, 48% of children under five years of age are stunted and 43% are underweight: almost 8 million children suffer from Severe Acute Malnutrition. Dr Prasad and colleagues are of the view that “the current thinking – that a centrally produced and processed Ready to use Therapeutic Foods should supplant the locally prepared indigenous […]

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