Indi Trehan, M.D., M.P.H., D.T.M.&H., Hayley S. Goldbach, Sc.B., Lacey N. LaGrone, M.D., Guthrie J. Meuli, B.S., Richard J. Wang, M.D., Kenneth M. Maleta, M.B., B.S., Ph.D., and Mark J. Manary, M.D. N Engl J Med 2013; 368:425-435January 31, 2013DOI: 10.1056/NEJMoa1202851 Abstract Background Severe acute malnutrition contributes to 1 million deaths among children annually. Adding […]
ABSTRACT Kwashiorkor, an enigmatic form of severe acute malnutrition, is the consequence of inadequate nutrient intake plus additional environmental insults. To investigate the role of the gut microbiome, we studied 317 Malawian twin pairs during the first 3 years of life. During this time, half of the twin pairs remained well nourished, whereas 43% became […]
In another randomized, double-blind, placebo-controlled, non-inferiority safety trial using a 2-mo course of daily iron Micronutrient Powder (MNP), or placebo powder (PP) conducted in 268 Bangladeshi children aged 12-24 mo with MAM (weight-for-age z score ≤ -2) and a hemoglobin concentration between 70 and 110 g/L, Lemaire and colleagues have reported that iron MNP is […]
A research has found that visible severe wasting failed to detect approximately half of the children admitted to hospital with severe acute malnutrition diagnosed anthropometrically The cross sectional study sought to determine the diagnostic value of visible severe wasting in identifying severe acute malnutrition among children aged 6 to 59.9 months admitted to one rural […]
A paper has demonstrated that an oral ciprofloxacin dose of 10 mg/kg three times daily (30 mg/kg/day) may be a suitable alternative antibiotic for the management of sepsis in severely malnourished children. Ciprofloxacin (10 mg/kg, 12 hourly) was administered either 2 h before or up to 2 h after feeds to Kenyan children hospitalized with […]
Nielsen J, Prudhon C, de Radigues X. The humanitarian response to the crisis in Darfur is considered the largest humanitarian operation in the world. Nielsen et al conducted a meta-analysis of 164 publicly available surveys to analyse trends in malnutrition and mortality in Dafur, Sudan. The results showed that Global Acute Malnutrition and Severe Acute […]
Wilford R, Golden K, Walker DG. The study showed that scaling-up CMAM within essential health services in Dowa District, Malawi was cost-effective and scaling up CMAM in similar contexts is also likely to be cost-effective This study assessed the cost-effectiveness of CMAM to prevent deaths due to severe acute malnutrition (SAM) among children under-five years […]
Hendricks KM. Nutr Rev. 2010 Jul;68(7):429-35. Abstract Undernutrition is a major contributor to child mortality and total global disease burden. Ready-to-use therapeutic food (RUTF) is recommended by the World Health Organization for community-based management of uncomplicated forms of severe acute malnutrition. New research has evaluated the role of RUTF for the prevention of childhood undernutrition. […]
Giugliani C, Duncan BB, Harzheim E, Breysse S, Jarrige L. A study has shown that short-term intervention with in-service supervision based on the WHO guidelines in a setting of limited resources contributed to a reduction in fatality rates from severe malnutrition The study measured the impact of practice review and in-service supervision based on WHO […]
Katherine Hampshire, Rachel Casiday, Kate Kilpatrick and Catherine Panter-Brick ABSTRACT In 2004–05, Niger suffered a food crisis during which global attention focused on high levels of acute malnutrition among children. In response, decentralised emergency nutrition programmes were introduced into much of southern Niger. Child malnutrition, however, is a chronic problem and its links with food […]